Comparison of reader agreement, correlation with liver biopsy, and time-burden sampling strategies for liver proton density fat fraction measured using magnetic resonance imaging in patients with obesity: a secondary cross-sectional study

Table 6 Intraclass coefficients (ICCs) of different sampling strategies

	Reader 1, 1st time vs. Reader 1, 2nd time				Reader 1, 1st time vs. Reader 2
Sampling strategies at segmental level (S1‒S8)
	Mean ICC	Highest ICC	Lowest ICC	Proportion with ICC > 0.995	Mean ICC	Highest ICC	Lowest ICC	Proportion with ICC > 0.995
1S-ROI	0.959	0.985	0.932	0%	0.956	0.972	0.932	0%
3S-ROI	0.982	0.988	0.973	0%	0.982	0.989	0.973	0%
1L-ROI	0.983	0.996	0.959	11% (1/9)	0.984	0.990	0.959	0%
3L-ROI	0.995	0.999	0.980	67% (6/9)	0.991	0.996	0.980	33% (3/9)

Sampling strategies at whole-liver level
	ICC	ICC
4S-ROI	0.994	0.991
4L-ROI	0.997	0.995
9S-ROI	0.995	0.993
27S-ROI	0.998	0.998
9L-ROI	0.998	0.998
27L-ROI	0.999	0.999

ISSN: 1471-2342