Reproducibility and feasibility of optic nerve diffusion MRI techniques: single-shot echo-planar imaging (EPI), readout-segmented EPI, and reduced field-of-view diffusion-weighted imaging

Table 6 Results of quantitative evaluations of anatomic measurements

	L-length (mm)	R-length (mm)	L-angle (°)	R-angle (°)
T2WI	2.44 ± 0.24	2.36 ± 0.18	169.61 ± 7.51	170.58 ± 7.12
rs-EPI DWI	2.25 ± 0.23	2.20 ± 0.23	165.24 ± 9.26	166.78 ± 11.02
ICCs^a	0.691	0.734	0.993	0.989
95%CI^b	0.341–0.855	0.426–0.877	0.986–0.997	0.977–0.995
rFOV DWI	2.21 ± 0.308	2.13 ± 0.28	165.64 ± 8.63	165.82 ± 11.24
ICCs^a	0.687	0.667	0.992	0.985
95%CI^b	0.334–0.853	0.281–0.846	0.984–0.996	0.969–0.993
ss-EPI DWI	2.17 ± 0.32	2.04 ± 0.31	158.92 ± 14.9	161.79 ± 17.72
ICCs^a	0.659	0.675	0.978	0.971
95%CI^b	0.275–0.840	0.297–0.850	0.954–0.990	0.939–0.987

rs-EPI DWI, readout-segmented echo-planar imaging diffusion-weighted imaging; rFOV, reduced field-of-view; ss-EPI, single-shot echo-planar imaging; L-length, the length of the left optic nerve; R-length, the length of the right optic nerve; L-angle, the maximum angle of the left optic nerve; R-angle, the maximum angle of the right optic nerve
^aAnatomic agreement of three sequences with T2w imaging, measured by intraclass correlation coefficients (ICCs)
^b95% confidence interval (CI) of ICCs. T2WI, T2 weighted imaging

ISSN: 1471-2342