Fig. 1

Activation measured in BOLD and pCASL finger-tapping scans at PIT and MGH scanning locations. Rendered Z-statistic images for each subject at each location for BOLD (a) and pCASL perfusion activation (b). Negative perfusion change is shown in blue, and positive is shown in red/yellow. Both BOLD and pCASL scan sequences showed activation in the motor cortex, and group mean images at each location were very similar. Signal changes for BOLD scans (c) at each location (PIT = blue, MGH = black) were significantly correlated between the two locations and with the finger-tapping task, shown in gray. Individual subject Pearson correlations with the task and within-subject are shown to the right, demonstrating excellent repeatability. Signal changes for pCASL scans (d) were significantly correlated with the tapping task at PIT and at MGH, and were significantly correlated between the two scanning locations, again as shown to the right