Evaluation of liver fibrosis in chronic hepatitis B patients with 2D shear wave elastography with propagation map guidance: a single-centre study

Table 6 Comparison of area under curve (AUC) to predict the disease severity

	AUC (95%Cl)	Cut-off levels	Sensitivity	Specificity	PPV	NPV	p value
F2
2D-SWE, kPa	0.956 (0.920–0.991)	8.2	0.926	0.788	0.786	0.927	< 0.001
2D-SWE, m/s	0.952(0.913–0.990)	1.65	0.926	0.741	0.775	0.905	< 0.001
APRI	0.657(0.549–0.765)	0.56	0.667	0.392	0.571	0.701	0.063
FIB-4	0.743(0.648–0.838)	0.82	0.741	0.588	0.471	0.710	< 0.001
F3
2D-SWE, kPa	0.978(0.945–1.000)	10.1	0.929	0.964	0.812	0.991	< 0.001
2D-SWE, m/s	0.982(0.961–1.000)	1.91	0.929	0.945	0.722	0.991	< 0.001
APRI	0.787(0.688–0.886)	0.86	0.883	0.705	0.375	0.905	0.001
FIB-4	0.765(0.601–0.929)	1.03	0.750	0.616	0.368	0.933	0.001

PPV Positive predictive value, NPV Negative predictive value, F2 Predict significant fibrosis, F3 Predict severe fibrosis, 2D-SWE Two dimensional shear wave elastography, kPa kilopascal, m/s meter/second, APRI Aspartate aminotransferase to platelet ratio index, FIB-4 Fibrosis-4

ISSN: 1471-2342