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Table 5 Liver stiffness measurement changing according to treatment regimen

From: Evaluation of liver fibrosis in chronic hepatitis B patients with 2D shear wave elastography with propagation map guidance: a single-centre study

 

Baseline versus week24

Baseline versus week48

Overall (n = 84)

ETV (n = 44)

TDF (n = 40)

p value

Overall (n = 84)

ETV (n = 44)

TDF (n = 40)

p value

LSM decrease

kPa value*

1.23 (0.3–2.8)

1.19 (0.2–2.4)

1.27 (0.2–2.8)

0.098

1.88 (0.1–4.8)

1.84 (0.1–3.5)

1.92 (0.1–4.8)

0.174

kPa %*

13.3 (3.1–22.8)

13.1 (2.1–22.8)

13.4 (2.3–21.7)

 

20.3 (2.1–37.8)

19.9 (2.7–36.5)

20.8 (2.1–37.8)

 

m/s value*

0.22 (0.03–0.31)

0.21 (0.02–0.30)

0.23 (0.02–0.31)

0.734

0.35 (0.03–0.44)

0.33 (0.03–0.39)

0.37 (0.04–0.44)

0.234

m/s %*

12.3 (1.9–21.9)

11.7 (1.9–20.6)

12.9 (2.6–21.9)

 

19.6 (1.4–38.6)

18.4 (1.4–35.3)

20.7 (1.5–38.6)

 

LSM decrease

 > 10%, n (%)

47 (55.9)

25 (56.8)

22 (55.0)

0.802

50 (59.5)

27 (61.4)

23 (57.5)

0.588

 > 20%, n (%)

9 (10.7)

5 (11.4)

4 (10.0)

0.659

22 (26.2)

12 (27.3)

10 (25.0)

0.915

  1. ETV Entecavir, TDF Tenofovir disoproxil fumarate, LSM Liver stiffness measurement, kPa Kilopascal, m/s Meter/second (*The mean kPa and m/s values measured with two dimensional share wave elastography and the minimum and maximum values are given)