Clinical utility of quantitative analysis of bone scintigraphy in detecting clinically active joint and high disease activity in patients with rheumatoid arthritis

Table 3 Comparison of joint uptake ratio and summed joint uptake ratio of the 28 joints between patients with high, moderate, and low disease activities and patients in comparison group

Disease activity	Joint uptake ratio		Summed joint uptake ratio of 28 joints
Disease activity	Clinically active joints	Non-affected joints	Summed joint uptake ratio of 28 joints
High (DAS28-ESR >5.1)	1.96 ± 1.13	1.38 ± 0.54	44.8 ± 5.8
Moderate (3.2< DAS28-ESR ≤5.1)	1.82 ± 0.96	1.12 ± 0.49	35.4 ± 7.5
Low (DAS28-ESR ≤3.2)	1.65 ± 0.86	0.99 ± 0.38	30.1 ± 5.6
P-value	0.115*	<0.001†	<0.001*
Comparison group patients with osteoarthritis	1.94 ± 0.90	0.88 ± 0.35	27.1 ± 3.3
P-value	0.273^‡	< 0.001^‡	< 0.001^‡

DAS28-ESR, disease activity score in 28 joints using erythrocyte sedimentation rate
^*P-values for analysis of variance between patients with high, moderate, and low disease activities
^†P-value for the Kruskal–Wallis test between patients with high, moderate, and low disease activities
^‡P-value for the Kruskal–Wallis test between patients with high, moderate, and low disease activities, and patients in comparison group with osteoarthritis

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