Table 3 Analysis of associations between MRI findings and effect of neoadjuvant chemotherapy
Variable | All, n (%) | pCR, n (%) | Non-pCR, n (%) | P value |
|---|---|---|---|---|
Breast type | ||||
Fibrous gland | 14 (28.0) | 3 (25.0) | 9 (23.7) | |
Compact | 30 (60.0) | 7 (58.3) | 5 (13.2) | |
Unknown | 6 | 2 | 4 | 0.936 |
Lesion types | ||||
Irregular | 26 (52.0) | 4 (33.3) | 22 (57.9) | |
Section distribution | 6 (12.0) | 3 (25.0) | 3 (7.9) | |
Circular | 8 (16.0) | 3 (25.0) | 5 (13.2) | |
Satellite lesions | 10 (20.0) | 2 (16.7) | 8 (21.1) | 0.244 |
Lesion location | ||||
Left | 24 (48.0) | 9 (75.0) | 15 (39.5) | |
Right | 26 (52.0) | 3 (25.0) | 23 (60.5) | 0.032 |
Lesion quadrant | ||||
Outer quadrant | 37 (74.0) | 9 (75.0) | 28 (73.7) | |
Upper inner | 7 (14.0) | 1 (8.3) | 6 (15.8) | |
Central | 5 (10.0) | 1 (8.3) | 4 (10.5) | |
Diffuse | 5 (10.0) | 1 (8.3) | 4 (10.5) | 0.886 |
BI-RADS rating | ||||
5 | 39 (78.0) | 9 (75.0) | 30 (78.9) | |
6 | 8 (16.0) | 2 (16.7) | 6 (15.8) | |
Unknown | 3 | 1 | 2 | 0.573 |
Pectoral muscle invasive | ||||
Yes | 13 (26.0) | 10 (83.3) | 3 (7.9) | |
No | 37 (74.0) | 2 (16.7) | 35 (92.1) | 0.398 |
Skin around areola invasive | ||||
Yes | 30 (60.0) | 5 (41.7) | 25 (65.8) | |
No | 20 (40.0) | 7 (58.3) | 13 (34.2) | 0.137 |
Crater nipple | ||||
Yes | 18 (36.0) | 2 (16.7) | 16 (42.1) | |
No | 32 (64.0) | 10 (83.3) | 22 (57.9) | 0.109 |
Internal mammary artery thickening | ||||
Yes | 30 (60.0) | 7 (58.3) | 23 (60.5) | |
No | 20 (40.0) | 5 (41.7) | 15 (39.5) | 0.892 |
Subareolar duct invasive | ||||
Yes | 18 (36.0) | 3 (25.0) | 15 (39.5) | |
No | 32 (64.0) | 9 (75.0) | 24 (63.2) | 0.109 |
Contralateral breast | ||||
Hyperplasia and adenosis | 30 (60.0) | 9 (75.0) | 21 (55.3) | |
Galactocele/fortified nodule | 14 (28.0) | 1 (8.3) | 12 (31.6) | |
No | 8 (16.0) | 2 (16.7) | 6 (15.8) | 0.202 |
Standard ADC change* | ||||
≤ 15% | 19 (38.0) | 1 (18.3) | 18 (47.4) | |
> 15% | 31 (62.0) | 11 (91.7) | 20 (52.6) | 0.015 |
Slow ADC change* | ||||
≤ 15% | 17 (36.2) | 2 (16.7) | 15 (42.9) | |
> 15% | 30 (63.8) | 10 (83.3) | 20 (57.1) | 0.103 |
Unknown | 3 | 1 | 2 | |
Tumor size change* | ||||
≤ 15% | 15 (30.0) | 1 (8.3) | 14 (36.8) | 0.06 |
> 15% | 35 (70.0) | 11 (91.7) | 24 (63.2) | 0 |
Fast ADC (10−3 mm2/s) | ||||
Value | 15.0 ± 14.4 | 13.9 ± 17.9 | 15.3 ± 13.1 | 0.785 |
Unknown | 6 | 1 | 5 | |
F value (%) | ||||
Value | 40.3 ± 27.8 | 47.3 ± 30.7 | 38.0 ± 26.9 | |
Unknown | 5 | 1 | 4 | 0.337 |
TIC type | ||||
Ascending | 6 (12.0) | 1 (8.3) | 5 (13.2) | |
Reduced | 15 (30.0) | 5 (41.7) | 10 (26.3) | |
Invariable | 29 (58.0) | 6 (50.0) | 23 (60.5) | 0.586 |