Table 7 Factors that may affect induced chemotherapy response of MM from multivariable logistic regression

ADC value (× 10^–3 mm²/s)

 0.3 < ADC ≤ 0.4

1.666 (3.439–8.069)

2.047 (1.063–1.593)

0.496 (0.631–2.789)*

0.136 (0.280–1.068)*

1.268 (0.445–1.116)*

 0.4 < ADC ≤ 0.5

1.917 (3.912–9.396)

0.110 (0.016–0.740)*

0.755 (0.755–1.227)*

1.811 (1.961–6.727)

0.496 (0.208–2.398)

 0.5 < ADC ≤ 0.6

3.817 (9.868–14.778)

0.692 (0.115–4.160)*

0.349 (0.129–0.974)*

4.432 (0.427–1.163)

1.219 (.0.598–1.530)

 0.7 < ADC ≤ 0.8

5.752 (2.178–15.198)

1.658 (0.376–7.304)*

0.798 (0.476–1.232)*

7.816 (0.920–1.335)

0.553 (0.181–0.910)*

 0.8 < ADC ≤ 0.9

1.121 (4.730–2.658)*

5.999 (1.761–20.428)

0.898 (1.497–10.687)

1.632 (3.132–8.499)

0.990 (0.202–1.392)*

 0.9 < ADC ≤ 1.0

0.651 (0.914–1.716)*

1.231 (0.339–4.466)

1.452 (3.523–5.986)*

0.608 (0.147–1.705)*

0.802 (0.779–1.252)*

 1.0 < ADC ≤ 1.1

3.906 (0.879–1.860)

3.171 (0.339–4.466)

1.501 (2.009–3.452)*

3.917 (3.890–7.998)

1.054 (0.371–1.529)*

 1.1 < ADC ≤ 1.2

2.925 (1.334–6.776)

2.496 (7.886–9.009)

1.453 (1.650–2.221)*

1.595 (3.435–4.667)

0.510 (3.445–8.956)*

 1.2 < ADC ≤ 1.3

1.334 (6.004–9.657)*

Reference

0.399 (0.111–1.433)

1.562 (1.312–9.673)*

0.110 (0.005–1.127)*

0.849 (0.445–1.956)*

 1.3 < ADC ≤ 1.4

1.679 (0.679–1.679)

1.957 (0.598–6.410)

1.024 (0.034–1.024)

4.008 (0.008–0.995)

1.389 (0.672–1.334)

 1.4 < ADC ≤ 1.5

1.355 (0.066–1.445)

1.769 (0.998–1.884)

1.886 (0.554–0.981)

0.776 (0.549–1.886)*

0.679 (0.630–1.086)

Gene variation

 p32 deletion

0.182 (2.397–35.169)

0.678 (2.586–4.089)*

3.725 (2.245–4.682)

1.733 (1.198–4.990)

0.645 (0.009–1.879)*

 P53 deletion

0.053 (1.609–10.206)*

0.942 (2.847–16.927)

3.725 (0.242–1.535)

0.359 (0.867–1.007)*

1.828 (1.905–3.445)*

 RB1 deletion

1.600 (0.856–2.991)

2.104 (1.072–4.129)

1.600 (0.768–3.331)

0.290 (0.065–2.005)

1.492 (0.067–1.992)*

 q21 amplification

0.050 (1.089–3.860)*

1.319 (0.639–2.723)**

4.239 (2.047–8.779)*

1.632 (0.494–5.392)

0.985 (0.181–5.355)*

 IGH rearrangement

0.640 (0.278–1.475)

0.824 (0.332–2.045)

0.205 (0.074–0.565)

0.993 (0.072–2.067)*

0.346 (0.064–1.729)*