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Table 4 Logistic regression results evaluating the predictors of clinically meaningful ADC value increase and decrease after chemotherapy

From: Correlations between apparent diffusion coefficient values of WB-DWI and clinical parameters in multiple myeloma

Parameters

ADC values increase (n = 91)a

ADC values decrease (n = 10)a

p value

Age

1.103 (0.920–1.322)

0.907 (0.756–1.087)

0.289

Gender

1.787 (0.164–19.475)

0.560 (0.051–6.089)

0.634

RISS stage

0.153 (0.008–3.074)

2.536 (1.132–5.684)

< 0.001b

Type of MM

0.394 (0.176–0.884)

6.542 (0.325–131.52)

0.005b

β2-MG

2.406 (1.094–5.294)

0.416 (0.189–0.914)

0.002b

Albumin

0.955 (0.795–1.146)

1.048 (0.872–1.258)

0.619

LDH

1.007 (0.977–1.038)

0.993 (0.964–1.023)

0.646

p53 deletion

1.257 (0.022–71.310)

0.796 (0.014–45.143)

0.912

IGH rearrangement

1.036 (0.978–2.012)

1.074 (1.005–1.995)

0.007b

q21 amplification

0 (0 to + ∞)

0 (0 to + ∞)

0.997

RB1 deletion

8.963 (0.167–48.145)

0.112 (0.002–5.980)

0.280

p32 deletion

62.549 (0.120–32.659)

0.560 (0.051–6.098)

0.634

  1. ADC apparent diffusion coefficient, LDH lactic dehydrogenase, MM multiple myeloma, RISS revised international staging system
  2. aThe values are given as the odds ratio, with 95% confidence interval in parentheses
  3. bSignificant difference