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Table 4 Logistic regression results evaluating the predictors of clinically meaningful ADC value increase and decrease after chemotherapy

From: Correlations between apparent diffusion coefficient values of WB-DWI and clinical parameters in multiple myeloma

Parameters ADC values increase (n = 91)a ADC values decrease (n = 10)a p value
Age 1.103 (0.920–1.322) 0.907 (0.756–1.087) 0.289
Gender 1.787 (0.164–19.475) 0.560 (0.051–6.089) 0.634
RISS stage 0.153 (0.008–3.074) 2.536 (1.132–5.684) < 0.001b
Type of MM 0.394 (0.176–0.884) 6.542 (0.325–131.52) 0.005b
β2-MG 2.406 (1.094–5.294) 0.416 (0.189–0.914) 0.002b
Albumin 0.955 (0.795–1.146) 1.048 (0.872–1.258) 0.619
LDH 1.007 (0.977–1.038) 0.993 (0.964–1.023) 0.646
p53 deletion 1.257 (0.022–71.310) 0.796 (0.014–45.143) 0.912
IGH rearrangement 1.036 (0.978–2.012) 1.074 (1.005–1.995) 0.007b
q21 amplification 0 (0 to + ∞) 0 (0 to + ∞) 0.997
RB1 deletion 8.963 (0.167–48.145) 0.112 (0.002–5.980) 0.280
p32 deletion 62.549 (0.120–32.659) 0.560 (0.051–6.098) 0.634
  1. ADC apparent diffusion coefficient, LDH lactic dehydrogenase, MM multiple myeloma, RISS revised international staging system
  2. aThe values are given as the odds ratio, with 95% confidence interval in parentheses
  3. bSignificant difference