Correlations between apparent diffusion coefficient values of WB-DWI and clinical parameters in multiple myeloma

BMC Medical Imaging

Table 3 Within-subjects ADC value change after chemotherapy

Parameters	Baseline visit	After 4-course chemotherapy	p value
ADC value (× 10^–3 mm²/s)	0.8556 (0.7130–1.361)	1.0076 (0.8817–1.3336)	< 0.001^a
Therapeutic response
CR	0.8561 (0.7890–1.3884)	1.1330 (0.9887–1.3883)	< 0.001^a
sCR	0.6772 (0.5985–0.9066)	0.9756 ± 0.2724	< 0.001^a
PR	0.8673 (0.7912–1.3301)	1.0961 ± 0.2724	< 0.001^a
VGPR	0.9555 ± 0.3326	1.0667 ± 0.2537	0.004^a
SD	1.3883 (0.8290–1.3891)	1.2588 ± 0.2467	0.151
PD	0.8504 ± 0.0602	1.0206 ± 0.8934	0.089
Plasma cell infiltration (%)	44.35 ± 23.11	5.01 ± 7.62	< 0.001^a
Albumin (g/L)	34.36 ± 7.31	37.44 ± 7.03	< 0.001^a
LDH (U/L)	222.41 ± 85.29	227.94 ± 48.14	0.570
β2 microglobulin (μg/mL)	8.75 ± 7.15	4.27 ± 3.00	< 0.001^a

ADC apparent diffusion coefficient, CR complete response, LDH lactic dehydrogenase, PD progressive disease, PR partial response, sCR strict complete response, SD sable disease, VGPR vary good partial response
^aSignificant difference

ISSN: 1471-2342