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Table 3 Injections details by GBCAa

From: Patterns of use, effectiveness and safety of gadolinium contrast agents: a European prospective cross-sectional multicentre observational study

 

Totala (N = 2118)

Clariscan (n = 1513)

Dotarem (n = 356)

Gadovist (n = 237)

Mean volume, mL, mean

14.2 (3.4)

15.0 (2.6)

14.2 (3.2)

8.5 (2.9)

Mean dose, mmol/kg, mean (SD)

0.10 (0.02)

0.10 (0.02)

0.10 (0.02)

0.12 (0.04)

Mean dose by type of procedure, mmol/kg, mean (SD)

 MRI

0.10 (0.02)

0.10 (0.02)

0.10 (0.02)

0.11 (0.02)

  CNS

0.10 (0.02)

0.10 (0.01)

0.10 (0.01)

0.11 (0.02)

  Organ/whole body

0.10 (0.02)

0.10 (0.02)

0.10 (0.02)

0.11 (0.03)

 MRAb

0.13 (0.04)

0.11 (0.03)

0.13 (0.04)

0.18 (0.04)

Dose category in mmol/kg, n (%)

  ≤ 0.1

1182 (55.8)

887 (58.6)

208 (58.4)

80 (33.8)

  > 0.1–0.2

919 (43.4)

623 (41.2)

147 (41.3)

144 (60.8)

  > 0.2–0.3

17 (0.8)

3 (0.2)

1 (0.3)

13 (5.5)

 Injector use, n (%)

1362 (64.3)

998 (66.0)

209 (58.7)

146 (61.6)

 Subsequent saline injection, n (%)

1461 (69.0)

1032 (68.2)

253 (71.1)

167 (70.5)

 Saline injection volume, mL, mean (SD)

17.2 (8.3)

15.6 (8.6)

21.9 (7.9)

19.8 (1.7)

Field strength

 1.5 T

1909 (90.1)

1391 (91.9)

311 (87.4)

207 (87.3)

 3 T

208 (9.8)

122 (8.1)

45 (12.6)

29 (12.2)

  > 3 T

1 (0.0)

0 (0.0)

0 (0.0)

1 (0.4)

  1. CNS central nervous system, GBCA gadolinium-based contrast agent, MRA magnetic resonance angiography, MRI magnetic resonance imaging, SD standard deviation
  2. aData for ProHance are not shown separately owing to the low number of patients (n = 12 [0.6%])
  3. bMRA type of procedures include procedures as angiography only and combined MRI/MRA procedures