A PET imaging study of the brain changes of glucose metabolism in patients with temporal lobe epilepsy and depressive disorder

Table 5 Summary of difference in glucose metabolic uptake values in brain regions between epilepsy with depression group and epilepsy without depression group

Brain regions	x	y	z	Number of voxels	Z value	P
TLE with depression < TLE without depression
Top of inferior frontal gyrus of left inferior frontal lobe	44	48	14	463	3.62	< 0.001
Left inferior frontal gyrus	42	− 12	− 42	154	3.16	< 0.001
Left temporal lobe	62	− 2	− 10	778	3.03	0.001
Left fusiform gyrus	64	− 40	− 16	82	2.95	0.002
TLE with depression > TLE without depression
Left inferior frontal gyrus	42	14	30	118	3.37	< 0.001
Right visual joint cortex	− 28	− 80	12	78	2.69	0.004
Right visual joint cortex	− 16	− 72	− 10	51	2.67	0.004
Right superior posterior - cingulate cortex	− 12	− 48	38	38	2.67	0.004
Right prefrontal lobe	− 24	20	42	39	2.62	0.004
Right secondary somato- sensory cortex	− 64	− 38	26	49	2.58	0.005

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