Table 3 Clinical characteristics and brain MRI findings of patients with DOL
From: Methadone-induced encephalopathy: a case series and literature review
Number | Age/ Sex | Toxic agent | Clinical presentation in relapse phase | Time to relapse after initial intoxication | Initial imaging | Delayed phase brain MRI findings | DWI and ADC |
|---|---|---|---|---|---|---|---|
9 | 47 yr, M | Methadone | Disorientation, seizure like activity | 9 days | No | Confluent bilateral symmetrical cerebral white matter T2 and FLAIR hyperintensity with sparing of sub cortical U-fibers | No restriction |
10 | 49 yr, M | Methadone | Confusion | 18 days | No | Confluent bilateral symmetrical cerebral white matter T2 and FLAIR hyperintensity with sparing of sub cortical U-fibers | No restriction |