Fig. 4
From: Methadone-induced encephalopathy: a case series and literature review
Axial (a) T2 and (b) FLAIR sequences in a 47-year-old male with DOE (patient number 9) above the ventricular level show confluent bilateral symmetrical cerebral white mater hyperintensity with sparing of subcortical U-fibers. Axial (c) DWI and (d) ADC sequences also show T2 shine through phenomenon without any evidence of diffusion restriction