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Table 3 ROC analyses of the significant parameters of the contrast-enhancing tumor to differentiate HGGs from SBMs

From: Differentiation between high-grade gliomas and solitary brain metastases: a comparison of five diffusion-weighted MRI models

Parameters

Cutoff value

AUC (95% CI)

Sensitivity (95% CI)

Specificity (95% CI)

Accuracy (95% CI)

DTI

 RD (10–3 mm2/s)

0.597

0.733(0.580, 0.887)

0.700(0.457, 0.872)

0.667(0.431, 0.845)

0.683(0.519, 0.819)

 MD (10–3 mm2/s)

0.797

0.686(0.522, 0.850)

0.900(0.669, 0.982)

0.428(0.226, 0.656)

0.658(0.494, 0.799)

 FA

0.287

0.731(0.567, 0.894)

0.700(0.457, 0.872)

0.810(0.574, 0.937)

0.756(0.597, 0.876)

DKI

 RDk (10–3 mm2/s)

1.106

0.760(0.613, 0.906)

0.950(0.730, 0.997)

0.476(0.264, 0.697)

0.707(0.545, 0.839)

 MDk (10–3 mm2/s)

1.084

0.745(0.593, 0.898)

0.850(0.611, 0.960)

0.619(0.387, 0.810)

0.732(0.571, 0.858)

 FAk

0.255

0.711(0.544, 0.877)

0.750(0.506, 0.904)

0.667(0.431, 0.845)

0.707(0.545, 0.839)

MAP

 MSD (10−5mm2)

24.688

0.736(0.683, 0.888)

0.950(0.730, 0.997)

0.428(0.226, 0.656)

0.683(0.519, 0.819)

 QIV (10−10mm5)

75.891

0.688(0.524, 0.852)

0.900(0.669, 0.982)

0.428(0.226, 0.656)

0.658(0.494, 0.799)

NODDI

 Viso

0.158

0.871(0.756, 0.987)

0.950(0.730, 0.997)

0.762(0.524, 0.909)

0.854(0.708, 0.944)

 ODI

0.409

0.770(0.621, 0.919)

0.800(0.557, 0.934)

0.667(0.431, 0.845)

0.732(0.571, 0.858)

  1. CI confidence interval