Skip to main content

Table 1 Clinical characteristics of the RT-PCR-negative and RT-PCR-positive groups

From: A model based on CT radiomic features for predicting RT-PCR becoming negative in coronavirus disease 2019 (COVID-19) patients

Variables Total (n = 203) Training dataset (n = 141) Testing dataset (n = 62)
Negative (n = 122) Positive (n = 81) p Negative (n = 85) Positive (n = 56) p Negative (n = 37) Positive (n = 25) p
General characteristics
 Age (years) 52 (41, 58) 49 (39, 57) 0.325 52 (41, 61) 51 (39, 58) 0.551 52 (41, 56) 46 (38, 56) 0.315
 Gender    0.343    0.191    0.800
 Female, n (%) 70 (57.38) 41 (50.62)   49 (57.65) 26 (46.43)   21 (56.76) 15 (60.00)  
 Male, n (%) 52 (42.62) 40 (49.38)   36 (42.35) 30 (53.57)   16 (43.24) 10 (40.00)  
 Time interval from symptoms onset to CT exams (days) 23 (18, 30) 16 (10, 22) < 0.001 22 (18, 30) 17 (11, 22) < 0.001 25.16 ± 8.45 15.52 ± 7.51 < 0.001
Comorbidities
 Diabetes, n (%) 9 (7.38) 1 (1.23) 0.099 7 (8.24) 1 (1.79) 0.212 2 (5.41) 0 (0.00) 0.511
 Hypertension, n (%) 20 (16.39) 10 (12.35) 0.426 13 (15.29) 9 (16.07) 0.901 7 (18.92) 1 (4.00) 0.183
 Cardiovascular disease, n (%) 1 (0.82) 1 (1.23) 1.000 1 (1.18) 1 (1.79) 1.000 0 (0.00) 0 (0.00) 1.000
 COPD, n (%) 4 (3.28) 2 (2.47) 0.929 2 (2.35) 1 (1.79) 0.713 2 (5.41) 1 (4.00) 0.726
 Chronic liver disease, n (%) 1 (0.82) 0 (0.00) 1.000 1 (1.18) 0 (0.00) 1.000 0 (0.00) 0 (0.00) 1.000
 Cancers, n (%) 3 (2.46) 1 (1.23) 0.921 1 (1.18) 1 (1.79) 1.000 2 (5.41) 0 (0.00) 0.511
Vital signs*
 Heart rate (beats/minute) 83 (76, 90) 85 (76, 90) 0.650 83 (74, 90) 85 (78, 89) 0.432 84.51 ± 10.90 83.40 ± 14.06 0.727
 Systolic blood pressure (mmHg) 127 (121, 135) 128 (120, 134) 0.637 126 (121, 133) 129 (121, 135) 0.822 129.43 ± 11.90 126.40 ± 12.53 0.339
 Diastolic blood pressure (mmHg) 78 (74, 84) 79 (74, 84) 0.621 78 (73, 84) 79 (72, 85) 0.420 79 (75, 87) 80 (76, 83) 0.841
 Respiratory rate (times/minute) 19 (18, 20) 19 (18, 20) 0.430 19 (18, 20) 19 (18, 20) 0.703 19 (18, 20) 19 (19, 20) 0.393
 Blood oxygen saturation (%) 96 (96, 97) 96 (96, 98) 0.887 96 (96, 97) 96 (96, 98) 0.654 97 (96, 98) 96 (96, 97) 0.621
Laboratory indicators*
 White blood cell count (× 109/L) 5.19 (4.62, 6.27) 5.10 (4.18, 5.86) 0.194 5.16 (4.53, 6.27) 5.00 (4.11, 5.61) 0.298 5.40 (4.75, 6.23) 5.19 (4.40, 6.18) 0.478
 Neutrophil count (× 109/L) 3.13 (2.66, 3.75) 2.79 (2.34, 3.46) 0.061 3.14 (2.46, 3.73) 2.83 (2.33, 3.46) 0.166 3.11 (2.72, 3.87) 2.79 (2.31, 3.49) 0.192
 Lymphocyte count (× 109/L) 1.64 (1.33, 1.97) 1.66 (1.30, 2.01) 0.964 1.58 (1.33, 1.91) 1.60 (1.26, 2.00) 0.982 1.76 (1.43, 2.02) 1.78 (1.43, 2.06) 0.914
 Hemoglobin count (g/L) 127 (118, 140) 129 (118, 139) 0.576 126.89 ± 16.99 131.46 ± 15.33 0.107 131 (121, 141) 122 (115, 133) 0.092
 Platelet count (× 109/L) 232 (180, 279) 219 (183, 283) 0.469 226 (177, 281) 219 (172, 263) 0.565 240 (187, 277) 215 (191, 288) 0.651
 NLR 1.83 (1.49, 2.40) 1.77 (1.34, 2.16) 0.160 1.91 (1.43, 2.50) 1.79 (1.36, 2.25) 0.357 1.82 (1.57, 2.13) 1.62 (1.24, 2.02) 0.187
  1. Bold with p value < 0.05. Categorical variables are presented as numbers (percentages). Quantitative variables are presented as the mean ± standard deviation or median (25% percentile, 75% percentile) according to normality test results
  2. COPD chronic obstructive pulmonary disease, NLR neutrophil/lymphocyte ratio
  3. *Normal range: heart rate, 60–100 beats/minute; Systolic blood pressure, 90–140 mmHg; Diastolic blood pressure, 60–90 mmHg; Respiratory rate, 12–20 times/minute; Blood oxygen saturation, 95–100%; White blood cell count, 3.50–9.50 × 109/L; Neutrophil count, 1.80–6.30 × 109/L; Lymphocyte count, 1.10–3.20 × 109/L; Hemoglobin count, 130–175 g/L; Platelet count, 125–350 × 109/L