Table 4 Influence of neoadjuvant chemotherapy on tumor size measurements
Sequence (n = cases)a | Median (IQR) histopathological diameter (cm) | Median (IQR) MRI diameter (cm) Reader 1 | Median (IQR) difference (cm) Reader 1 | Median (IQR) Absolute error (cm) Reader 1 | p-value Reader 1 |
|---|---|---|---|---|---|
Reader 2 | Reader 2 | Reader 2 | Reader 2 | ||
Neoadjuvant chemotherapy | |||||
Axial T1w precontrast (n = 15) | 5.8 (2.2) | 3.8 (3.4) | −1.0 (1.9) | 1.0 (1.9) | 0.001 |
3.9 (3.5) | −0.8 (2.3) | 1.1 (2.2) | 0.003 | ||
3D T1w precontrast (n = 15) | 5.8 (2.2) | 5.2 (2.9) | −0.3 (1.8) | 0.7 (1.0) | 0.224 |
5.2 (2.6) | −0.5 (2.1) | 0.8 (1.2) | 0.271 | ||
Axial T1w postcontrast (n = 18) | 5.9 (3.9) | 4.3 (4.5) | −1.0 (2.1) | 1.1 (1.8) | 0.001 |
4.6 (4.4) | −1.0 (1.3) | 1.0 (1.2) | < 0.001 | ||
3D T1w postcontrast (n = 18) | 5.9 (3.9) | 5.3 (3.9) | −0.1 (1.3) | 0.7 (0.8) | 0.369 |
5.2 (4.2) | −0,3 (1.7) | 0.7 (1.1) | 0.387 | ||
Axial T2w TSE (n = 19) | 5.8 (3.8) | 4.1 (3.6) | −1.5 (1.9) | 1.5 (1.8) | < 0.001 |
4.2 (3.6) | −1.3 (1.8) | 1.4 (1.7) | 0.001 | ||
3D T2w TSE (n = 19) | 5.8 (3.8) | 5.1 (3.4) | −0.4 (1.7) | 0.6 (1.2) | 0.101 |
5.2 (3.5) | −0.1 (1.3) | 0.6 (1.3) | 0.341 | ||
Axial DWI (n = 14) | 6.2 (4.0) | 4.8 (6.4) | −1.5 (2.1) | 1.5 (2.0) | 0.001 |
4.6 (5.8) | −1.4 (2.1) | 1.4 (2.0) | 0.001 | ||
3D DWI (n = 14) | 6.2 (4.0) | 5.2 (5.0) | −0.5 (1.7) | 0.7 (1.2) | 0.100 |
5.4 (5.0) | −0.6 (1.6) | 0.9 (1.1) | 0.094 | ||
No neoadjuvant chemotherapy | |||||
Axial T1w precontrast (n = 16) | 5.5 (4.9) | 5.0 (3.5) | −1.1 (1.8) | 1.1 (1.7) | < 0.001 |
5.3 (4.1) | −1.0 (1.4) | 1.0 (1.4) | < 0.001 | ||
3D T1w precontrast (n = 16) | 5.5 (4.9) | 5.7 (5.2) | −0.3 (1.4) | 0.6 (0.5) | 0.792 |
5.7 (5.3) | −0.2 (1.5) | 0.7 (0.6) | 0.308 | ||
Axial T1w postcontrast (n = 19) | 5.8 (5.2) | 5.3 (4.1) | −0.9 (1.8) | 1.1 (1.2) | 0.002 |
5.3 (4.3) | −0.9 (1.7) | 1.0 (1.3) | 0.001 | ||
3D T1w postcontrast (n = 19) | 5.8 (5.2) | 6.2 (5.7) | 0.1 (1.5) | 0.6 (0.6) | 0.658 |
6.0 (5.5) | −0.1 (1.3) | 0.7 (0.9) | 0.914 | ||
Axial T2w TSE (n = 19) | 5.8 (5.2) | 5.0 (4.1) | −0.8 (1.5) | 1.0 (1.5) | 0.001 |
5.2 (3.9) | −0.9 (1.6) | 1.0 (1.6) | 0.003 | ||
3D T2w TSE (n = 19) | 5.8 (5.2) | 6.2 (5.7) | 0.2 (1.5) | 0.7 (0.8) | 0.686 |
6.2 (5.7) | −0.1 (1.3) | 0.5 (0.5) | 0.521 | ||
Axial DWI (n = 12) | 8.1 (6.4) | 6.6 (4.7) | −1.1 (2.7) | 1.4 (2.4) | 0.043 |
6.8 (4.8) | −1.0 (2.6) | 1.4 (2.1) | 0.062 | ||
3D DWI (n = 12) | 8.1 (6.4) | 9.0 (6.2) | −0.2 (1.6) | 0.7 (1.2) | 0.745 |
9.5 (6.3) | 0.0 (1.4) | 0.6 (1.0) | 0.984 | ||