Skip to main content

Table 4 Diagnostic Performance of BUS and/or CEUS for Differentiating between HAE and ICC

From: Differential diagnosis between hepatic alveolar echinococcosis and intrahepatic cholangiocarcinoma with conventional ultrasound and contrast-enhanced ultrasound

  Sensitivitya 95% CIa Specificitya 95% CIa AUC 95% CI LR+ LR-
BUS + CEUS score
 Training set 82.5 67.2–92.7 86.4 72.6–94.8 0.913 0.832–0.964 6.05 0.20
 Testing set 80.0 56.3–94.3 81.3 54.4–96.0 0.905 0.760–0.977 4.27 0.25
  ≤ 5.0 cm 72.7 49.8–89.3 91.7 73.0–99.0 0.912 0.791–0.975 8.73 0.30
BUS score
 Training set 67.5 50.9–81.4 100.0 92.0–100.0 0.886 0.798–0.945 NA 0.33
 Testing set 60.0 36.1–80.9 100.0 79.4–100.0 0.925 0.786–0.986 NA 0.40
  ≤ 5.0 cm 45.5 24.4–67.8 100.0 85.8–100.0 0.875 0.744–0.954 NA 0.55
CEUS score
 Training set 82.5 67.2–92.7 65.9 50.1–79.5 0.777 0.673–0.861 2.42 0.27
 Testing set 65.0 40.8–84.6 68.9 41.3–89.0 0.717 0.543–0.854 2.08 0.51
  ≤ 5.0 cm 72.7 49.8–89.3 75.0 53.3–90.2 0.773 0.625–0.883 2.91 0.36
  1. a Numbers are percentages
  2. HAE Hepatic alveolar echinococcosis; ICC Intrahepatic cholangiocarcinoma; CEUS Contrast enhanced ultrasound; AUC Area under the curve; PPV Positive predictive value; NPV Negative predictive value