Table 3 Univariate and multivariate analysis using a cumulative logistic regression method to predict histologic upgrade to microinvasion and invasion

Age (old vs. young)

1.02 (1.00–1.05)

0.070

Biopsy method (US-CNB vs. SVAB)

2.78 (1.28–6.01)

0.009

Nuclear grade (grade 3 vs. grade 1–2)

7.51 (2.38–23.75)

< 0.001

Necrosis (present vs. absent)

1.74 (1.02–2.98)

0.044

ER (absent vs. present)

2.97 (1.63–5.38)

< 0.001

PR (absent vs. present)

3.53 (2.02–6.17)

< 0.001

2.40 (1.29–4.44)

0.006

HER2 (present vs. absent)

2.81 (1.62–4.87)

< 0.001

Ki-67 (high vs. low)

3.44 (1.98–6.00)

< 0.001

2.42 (1.30–4.50)

0.005

Mammographic calcification (present vs. absent)

1.70 (0.96–3.02)

0.072

BPE on MRI (minimal or mild vs. moderate or marked)

1.88 (1.00–3.55)

0.051

  Mass

8.81 (1.10–70.93)

0.041

8.84 (1.05–74.04)

0.045

NME

11.95 (1.50–95.20)

0.019

11.17 (1.35–92.36)

0.025