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Table 1 Clinicopathologic features of the DCIS, mIDC, and IDC lesions in the study cohort

From: The role of MRI and clinicopathologic features in predicting the invasive component of biopsy-confirmed ductal carcinoma in situ

 

DCIS (n = 112)

mIDC (n = 50)

IDC (n = 44)

P value

Age, years

48.6 ± 10.3

50.3 ± 11.5

52.1 ± 10.8

0.181

Biopsy method

   

0.028

 SVAB

28 (25.0)

6 (12.0)

4 (9.1)

 

 US-CNB

84 (75.0)

44 (88.0)

40 (90.9)

 

Surgery type

   

< 0.001

 Breast conserving

80 (71.4)

29 (58.0)

15 (34.1)

 

 Mastectomy

32 (28.6)

21 (42.0)

29 (65.9)

 

Nuclear grade

   

0.001

 1

15 (13.4)

4 (8.0)

1 (2.3)

 

 2

88 (78.6)

30 (60.0)

29 (65.9)

 

 3

9 (8.0)

16 (32.0)

14 (31.8)

 

Necrosis

   

0.073

 Present

54 (47.4)

33 (66.0)

27 (61.4)

 

 Absent

58 (51.8)

17 (34.0)

17 (38.6)

 

Pathologic tumor size (cm)

2.0 ± 1.6

3.7 ± 2.3

4.5 ± 2.4

< 0.001

Estrogen receptor

   

< 0.001

 Positive

103 (92.0)

26 (52.0)

34 (77.3)

 

 Negative

9 (8.0)

24 (48.0)

10 (22.7)

 

Progesterone receptor

   

< 0.001

 Positive

95 (84.8)

21 (42.0)

26 (59.1)

 

 Negative

17 (15.2)

29 (58.0)

18 (40.9)

 

HER2

   

< 0.001

 Positive

20 (17.9)

30 (60.0)

16 (36.4)

 

 Negative

92 (82.1)

20 (40.0)

28 (63.6)

 

Ki-67

   

< 0.001

 High (≥20%)

24 (21.4)

24 (48.0)

24 (54.5)

 

 Low (< 20%)

88 (78.6)

26 (52.0)

20 (45.5)

 
  1. Data values indicate the number of patients (with percentages in parentheses), or the mean ± standard deviation.
  2. DCIS ductal carcinoma in situ; mIDC microinvasive ductal carcinoma; IDC invasive ductal carcinoma; SVAB stereotactic vacuum-assisted biopsy; US-CNB US-guided core needle biopsy; HER2 human epidermal growth factor receptor 2