Fig. 1

Summary of wb-MRI performance versus standard clinical work-up and PET-CT in diagnosing infectious foci in patients with FUO. A bar graph of diagnostic tests a shows the number of patients receiving each respective clinical test. b Altogether 46% of infectious foci were found by wb-MRI alone compared to standard clinical tests. PET-CT found the same 4/6 infectious foci as wb-MRI in patients on whom both examinations were performed (not shown in the graph). Note that the infectious foci diagnosed by standard diagnostics alone (12%) were all cases of endocarditis revealed by cardiac ultrasound. In 50% of patients a change of clinical management immediately followed the wb-MRI c and in all cases in which a focus was found in any imaging modality (75%) the wb-MRI was directly involved in the final diagnosis d