Fig. 3From: Serial MRI studies over 12 months using manual and atlas-based region of interest in patients with amyotrophic lateral sclerosisManual ROI of the CST at the pons and PLIC. This Figure illustrates in two different axial planes for individual patient FA maps and the mask applied for the manual ROI for the pontine CST (left) and posterior limb of internal capsule, PLIC (right). With this method, only the voxels from one plane are included in the mask of the ROIBack to article page