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Table 2 Comparisons of each Parameters between Malignant and Benign Groups

From: Differentiation of soft tissue and bone sarcomas from benign lesions utilizing 18F-FDG PET/CT-derived parameters

Characteristic

Grouping

Total

Statistical Magnitude

P value

Malignant

Benign

Age(y)

59 (55.8 ± 14.1)

56 (54.8 ± 13.6)

58.5 (55.3 ± 13.8)

Z = -0.112

0.911

Sex

   

χ2 = 1.322

0.336

 Male

23 (58.97%)

16 (41.03%)

39

  

 Female

16 (51.61%)

15 (48.39%)

31

  

FDG uptake

   

χ2 = 6.911

0.009

 Higher

30 (81.1%)

17 (51.5%)

47

  

 Opposite

7 (18.9%)

16 (48.5%)

23

  

FDG distribution

   

χ2 = 8.036

0.005

 Heterogeneously

28 (75.7%)

14 (42.4%)

42

  

 Homogeneously

9 (24.3%)

19 (57.6%)

28

  

Boundary

   

χ2 = 8.226

0.004

 Obscure

30 (81.1%)

16 (48.5%)

46

  

 Clear

7 (18.9%)

17 (51.5%)

24

  

Density

   

χ2 = 6.708

0.010

 Uneven

27 (73.0%)

14 (42.4%)

41

  

 Uniform

10 (27.0%)

19 (57.6%)

29

  

Size (cm)

7 (7.5 ± 4.2)

3.8 (4.8 ± 5.2)

5.3 (6.2 ± 4.9)

Z = -3.490

< 0.001

SUVmaxa

8.7 (12.4 ± 9)

4.7 (7 ± 5.2)

6.9 (9.8 ± 7.9)

Z = -3.507

< 0.001

MTVb(cm3)

36 (57.7 ± 54.9)

15 (18.8 ± 16.5)

24.8 (39.4 ± 45.6)

Z = -3.406

0.001

TLGc

251.4 (426.3 ± 513.8)

37.6 (81.1 ± 119.8)

102.4 (263.6 ± 417.7)

Z = -4.159

< 0.001

HFd

0.84 (1.39 ± 1.31)

0.54 (0.38 ± 0.35)

0.56 (0.92 ± 1.1)

Z = -4.171

< 0.001

  1. a for maximum standardized uptake value, b for metabolic tumor volume, c for total lesion glycolysis, d for heterogeneous factor, statistical description by n (%) or median (−χ ± s)