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Table 2 CBF in different brain regions among the PD, PPS, and HC groups

From: Discriminative pattern of reduced cerebral blood flow in Parkinson’s disease and Parkinsonism-Plus syndrome: an ASL-MRI study

Peak location (AAL-90)

MNI coordinate

No. of voxels

Peak

F-value

HC

PD

PPS

PD-HC

PPS-HC

PPS-PD

x

y

z

Mean/SD

Mean/SD

Mean/SD

p-value

p-value

p-value

SMA.L

− 2

24

60

481

3.73

43.54/11.98

42.59/10.87

29.04/10.15

0.794

< 0.001

0.001

THA.R

1

−16

5

313

3.74

58.83/12.32

54.01/11.62

42.38/12.21

0.229

< 0.001

0.006

FG_Med_Orb.L

0

64

−4

646

3.82

57.03/11.38

47.94/12.05

40.56/9.34

0.016

< 0.001

0.053

IFG_Tri.L

−52

20

2

580

3.88

46.62/4.65

41.28/9.29

35.15/7.07

0.034

< 0.001

0.017

MFG.L

−40

26

40

377

3.93

48.80/7.25

41.58/11.46

33.62/9.67

0.029

< 0.001

0.018

Cere_Crus2.R

50

−66

−50

622

4.25

31.52/10.35

19.45/13.53

14.58/6.15

0.001

< 0.001

0.182

CN. L

−10

4

12

457

4.56

33.61/5.34

29.48/4.19

24.93/6.11

0.020

< 0.001

0.012

  1. Abbreviations: CBF, cerebral blood flow; AAL, automated anatomical labeling; HC, healthy controls; PD, Parkinson’s disease; PPS, Parkinsonism-Plus syndrome; SMA, supplementary motor area; THA, thalamus; FG_Med_Orb, frontal medial orbital gyrus; IFG_Tri, triangle inferior frontal gyrus; MFG, middle frontal gyrus; Cere_Crus2, cerebellum_crus2; CN, caudate nucleus; L (R), left (right) hemisphere; SD, standard deviation