Fig. 3

CT images of four patients and corresponding ROIs were sampled from the whole cohort. (a) and (b) indicate stroke-free patients, whereas (c) and (d) indicate patients who suffered future strokes. Although the Rad scores vary considerably within the two groups, they are nearly indistinguishable to the naked eye. This suggests that Rad scores, as derived from selected radiomic features, quantitatively represent the latent heterogeneity of ROIs and further predict risk of future strokes. The above images were resized to a scale of 15 voxels/mm, and the intensity range was windowed by the interval [0, 100] for good visual effect. CT, computed tomography; ROI, region of interest