Table 3 Univariate and two multivariate logistic regression models for diagnosis of malignant lesion
From: Prospective evaluation of contrast-enhanced ultrasound of breast BI-RADS 3–5 lesions
Univariate association with malignancy | Multivariate association with malignancy Model 1 | Multivariate association with malignancy Model 2 | |||||||
|---|---|---|---|---|---|---|---|---|---|
n = 213 | Crude OR (95% CI) | p-value | n = 213 | adjusted OR (95% CI) | p-value | n = 213 | adjusted OR (95% CI) | p-value | |
Quantitative parameters | |||||||||
TTP (10 s) | 0.65 (0.50–0.84) | 0.001 | 213 | 0.78 (0.59–1.03) | 0.076 | – | – | – | |
WIS (1 dB/s) | 6 (1.71–21) | 0.005 | – | – | – | 213 | 1.6 (0.42–6.09) | 0.489 | |
PI (1 dB) | 1.04 (0.91–1.19) | 0.575 | – | – | – | – | – | – | |
AUC (10 dB x s) | 1.00 (0.97–1.02) | 0.698 | |||||||
Qualitative parameters | |||||||||
Type of vascularization | |||||||||
peripheral | 164 | 1.00 | ref. | – | – | – | – | – | – |
peripheral + central | 49 | 1.72 (0.89–3.33) | 0.110 | – | – | – | – | – | – |
Perfusion homogeneity | |||||||||
homogeneous | 14 | 1.00 | – | – | – | – | – | – | – |
heterogeneous | 199 | 2.91 (0.63–13.39) | 0.170 | – | – | – | – | – | – |
Enhancement degree | |||||||||
poor or absent | 78 | 1.00 | – | 78 | 1.00 | – | 78 | 1.00 | – |
intermediate | 70 | 4.96 (1.97–12.49) | 0.001 | 70 | 4.1 (1.6–10.47) | 0.003 | 70 | 4.83 (1.91–12.18) | 0.001 |
rich | 65 | 13.40 (5.35–33.59) | < 0.001 | 65 | 10.38 (4.04–26.72) | < 0.001 | 65 | 12.00 (4.57–31.52) | < 0.001 |