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Table 2 Quantitative and qualitative parameters of breast CEUS according to the type of the tumor

From: Prospective evaluation of contrast-enhanced ultrasound of breast BI-RADS 3–5 lesions

 

Benign lesions (n = 146)

Malignant lesions (n = 67)

p-value

Quantitative parameters

TTP (s)

    

< 0.001

  mean/ median/ range

29/ 25/ 4–152

 

20/ 18/ 4–70

  

WIS (dB/s)

    

< 0.001

  mean/ median/ range

0.13/ 0.04/ 0–1.64

 

0.24/ 0.14/ 0–1.63

  

PI (dB)

    

0.105

  mean/ median/ range

2.8/ 2/ 0.1–10.5

 

2.9/ 2.8/ 0–8.6

  

AUC (dB.s)

    

0.711

  mean/ median/ range

149/ 102/ 5–602

 

142/ 126/ 1–492

  

Qualitative parameters

n = 146

%

n = 67

%

 

Type of vascularization

    

0.117

  peripheral

117

80%

47

70%

 

  peripheral + central

29

20%

20

30%

 

Perfusion homogeneity

    

0.234

  homogeneous

12

8%

2

3%

 

  heterogeneous

134

92%

65

97%

 

Enhancement degree

    

< 0.001

  poor/absent

71

48.6%

7

10.4%

 

  intermediate

47

32.2%

23

34.3%

 

  rich

28

19.2%

37

55.2%

 
  1. Abbreviations: CEUS contrast-enhanced ultrasound; TI time intensity curves; TTP time to peak; WIS wash in slope; PI peak intensity; AUC area under curve