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Table 3 GSI quantitative parameters for differential diagnosis of glioma recurrence and treatment-related changes

From: Dual-energy spectral CT quantitative parameters for the differentiation of Glioma recurrence from treatment-related changes: a preliminary study

GSI Quantitative Parameters

AUC

Maximum Youden Index

Threshold of Parameters

Sensitivity (%)

Specificity (%)

PPV (%)

NPV (%)

Accuracy

Venous phase λHU

0.912 (0.812,1.012)

0.667

1.03

66.7 (56.7,76.7)

100.0 (90.0,110.0)

100.0 (90.0,110.0)

81.8 (71.8.91.8)

86.7 (76.7,96.7)

Venou phase Zeff

0.912 (0.810,1.014)

0.695

7.75

91.7 (81.5101.9)

77.8 (67.6,88.0)

73.3 (63.1,83.5)

93.3 (83.1103.5)

83.3 (73.1,93.5)

Venous phase Zeff-N

0.931 (0.843,1.019)

0.722

1.04

83.3 (74.5,92.1)

88.9 (80.1,97.7)

83.3 (74.5,92.1)

88.9 (80.1,97.7)

86.7 (77.9,95.5)

Venous phase IC

0.910 (0.810, 1.010)

0.695

2.85

91.7 (81.9101.5)

77.8 (68.0,87.6)

73.3 (63.5,83.1)

93.3 (83.5103.1)

83.3 (73.5,93.1)

  1. AUC Area under the receiver operating characteristic curve
  2. Data in parentheses are 95% confidence intervals (CIs)