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Table 3 GSI quantitative parameters for differential diagnosis of glioma recurrence and treatment-related changes

From: Dual-energy spectral CT quantitative parameters for the differentiation of Glioma recurrence from treatment-related changes: a preliminary study

GSI Quantitative ParametersAUCMaximum Youden IndexThreshold of ParametersSensitivity (%)Specificity (%)PPV (%)NPV (%)Accuracy
Venous phase λHU0.912 (0.812,1.012)0.6671.0366.7 (56.7,76.7)100.0 (90.0,110.0)100.0 (90.0,110.0)81.8 (71.8.91.8)86.7 (76.7,96.7)
Venou phase Zeff0.912 (0.810,1.014)0.6957.7591.7 (81.5101.9)77.8 (67.6,88.0)73.3 (63.1,83.5)93.3 (83.1103.5)83.3 (73.1,93.5)
Venous phase Zeff-N0.931 (0.843,1.019)0.7221.0483.3 (74.5,92.1)88.9 (80.1,97.7)83.3 (74.5,92.1)88.9 (80.1,97.7)86.7 (77.9,95.5)
Venous phase IC0.910 (0.810, 1.010)0.6952.8591.7 (81.9101.5)77.8 (68.0,87.6)73.3 (63.5,83.1)93.3 (83.5103.1)83.3 (73.5,93.1)
  1. AUC Area under the receiver operating characteristic curve
  2. Data in parentheses are 95% confidence intervals (CIs)