Fig. 1

Contrast-enhanced venous phase GSI images show that IC and spectral curve were significantly different in glioma recurrence and the normal reference brain parenchyma. a Contrast-enhanced 70-keV monochromatic image (L1: area, 54.16 mm2; mean CT value, 69.33 HU; L2: 54.16 mm2; mean CT value, 48.06 HU). b Iodine-based materialdecomposition. image shows that IC in glioma recurrence and the normal reference brain parenchyma were 0.915 mg/cm3. and 0.113 mg/cm3 (L1: area, 54.16 mm2; mean IC, 9.15 · 100 μg/cm3; L2: area, 54.16 mm2; mean IC, 1.13 · 100 μg/cm3). c Graph shows spectral HU curve of glioma recurrence (yellow) and the normal reference brain parenchyma (red), slope of the curve representing glioma recurrence is much higher than the normal reference brain parenchyma (1.75 vs. 0.20). d The pathology noted after the first operation indicated astrocytoma (Grade II). e A large of tumor cells showed diffused distribution in the smear; eosinophil, nuclear were marked atypia, and the pathologic diagnosis was glioblastoma (Grade IV). f The GFAP was positive