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Table 1 Comparison of mean values of the DCE-MRI indices between groups

From: Gadoxetate-enhanced dynamic contrast-enhanced MRI for evaluation of liver function and liver fibrosis in preclinical trials

MRI indices

Control group

Low-dose group

High-dose group

p value

Post-hoc analysisa

RLE-3

2.84 ± 0.29

1.96 ± 0.23

1.87 ± 0.18

<  0.001

1 vs 2, 1 vs 3

RLE-15

1.93 ± 0.34

1.67 ± 0.05

1.53 ± 0.29

<  0.001

1 vs 3

iAUC-3

6.54 ± 0.51

5.49 ± 0.37

5.20 ± 0.36

<  0.001

1 vs 2, 1 vs 3

iAUC-15

35.37 ± 3.07

28.25 ± 2.09

25.84 ± 2.92

<  0.001

1 vs 2, 1 vs 3

Emax

3.03 ± 0.26

2.28 ± 0.23

2.12 ± 0.20

<  0.001

1 vs 2, 1 vs 3

  1. aPairs with a statistically significant difference in post-hoc analysis. Here, 1 means control group, 2 means low-dose group, and 3 means high-dose group