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Fig. 1 | BMC Medical Imaging

Fig. 1

From: Gadoxetate-enhanced dynamic contrast-enhanced MRI for evaluation of liver function and liver fibrosis in preclinical trials

Fig. 1

Histopathology of the liver parenchyma. a Hematoxylin and eosin (H&E) stain and Masson’s trichrome (MT) stain at 200× magnification. The H&E stain demonstrates centrilobular necrosis and scattered inflammation which are more severe in high-dose group than low-dose group. In the MT stain, the liver fibrosis is depicted as the fibrous bands or septa with abundant collagen deposition which is stained as blue color. b Comparison of the collagen area (%) between groups. Asterisks (*) refer the pairs with a statistically significant difference. c Comparison of the ICG-R15 (%) between groups. Asterisks (*) refer the pairs with a statistically significant difference

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