TY - JOUR AU - Huh, Jimi AU - Ham, Su Jung AU - Cho, Young Chul AU - Park, Bumwoo AU - Kim, Bohyun AU - Woo, Chul-Woong AU - Choi, Yoonseok AU - Woo, Dong-Cheol AU - Kim, Kyung Won PY - 2019 DA - 2019/11/15 TI - Gadoxetate-enhanced dynamic contrast-enhanced MRI for evaluation of liver function and liver fibrosis in preclinical trials JO - BMC Medical Imaging SP - 89 VL - 19 IS - 1 AB - To facilitate translational drug development for liver fibrosis, preclinical trials need to be run in parallel with clinical research. Liver function estimation by gadoxetate-enhanced dynamic contrast-enhanced MRI (DCE-MRI) is being established in clinical research, but still rarely used in preclinical trials. We aimed to evaluate feasibility of DCE-MRI indices as translatable biomarkers in a liver fibrosis animal model. SN - 1471-2342 UR - https://doi.org/10.1186/s12880-019-0378-5 DO - 10.1186/s12880-019-0378-5 ID - Huh2019 ER -