Table 3 Baseline findings of the three patient groups of the granulomatosis with polyangiitis cohort
No osteitis | Stable | Progressive | |
|---|---|---|---|
Number of patients; n (%) | 45 (100) | 31 (100) | 45 (100) |
Demographics | |||
Females; n (%) | 22 (49) | 13 (42) | 21 (47) |
Age in years at diagnosis; median (range) | 46 (16 - 86) | 46 (9 - 78) | 50 (13 - 78) |
Age in years at baseline CT; median (range) | 46 (17 - 85) | 52 (16 - 79) | 51 (13 - 80) |
Years from diagnosis to baseline CT; median (range) | <1 (–4 - 18) | 1 (–1 - 25) | <1 (–7 - 20) |
Observation time in years; median (range) | 4.4 (1.1 - 13) | 6.1 (1.1 - 13) | 6.8 (1.2 - 15) |
Number of CT scans analysed per patient; median (range) | 4 (3 - 10) | 6 (3 - 17) | 6 (3 - 14) |
Clinical data | |||
PR3-ANCA; n (%) | 40 (89) | 25 (81) | 37 (82) |
MPO-ANCA; n (%) | 3 (7) | 4 (13) | 6 (13) |
Paranasal sinus surgery; n (%) | 4 (9) | 7 (23) | 22 (49) |
Local pain; n (%) | 13 (29) | 8 (26) | 18 (40) |
Nasal congestion; n (%) | 22 (49) | 18 (58) | 27 (60) |
Epistaxis; n (%) | 11 (24) | 13 (42) | 16 (36) |
Nasal crusts; n (%) | 12 (27) | 9 (29) | 9 (20) |
CT findings | |||
GOSS >0; n (%) | 0 (0) | 24 (77) | 34 (76) |
Destruction score >0; n (%) | 4 (9) | 11 (35) | 18 (40) |
LM-score >0; n (%) | 28 (62) | 27 (87) | 43 (96) |