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Table 3 Intraoperative course and pathological results

From: The role of ultrasound in the diagnosis of the coexistence of primary hyperparathyroidism and non-medullary thyroid carcinoma

Characteristics

Patient

1

2

3

4

5

6

7

Intraoperative findings

Lesion A1 in the left thyroid lobe, toughLesion A2 (about 1 cm) posterior to the right thyroid lobe, soft

Lesion B1 (2x3cm) in the left thyroid zone, adherence to adjacent tissueLesion B2 inferior pole of the right thyroid lobeLesion B3 in the right thyroid lobe

Lesion C1 in the right thyroid lobe, toughLesion C2 posterior to the right thyroid lobe

Lesion D1 in the left thyroid lobe, toughLesion D2 (about 1 cm) posterior to the left thyroid lobe, soft

Several nodules in both thyroid lobe, toughMultiple enlarged lymph nodes in the cervical central regionLesion E posterior to the right thyroid lobe

Lesion F1 in the left thyroid lobe, toughLesion F2 (about 1 cm) posterior to the left thyroid lobe

Lesion G1 (2.5 cm) in the right thyroid lobe, toughLesion G2 (4 cm) in the left thyroid lobe

Section frozen results

Lesion A1: PTCLesion A2: Parathyroid adenoma

Lesion B1: Wait for final pathologic resultLesion B2: Parathyroid adenomaLesion B3: PTMC (about 0.3 cm)

Lesion C1: PTC (0.4 cm)Lesion C2: Highly suspected parathyroid adenoma, wait for final pathologic result

Lesion D1: PTC (1.3 × 1 × 0.6 cm)Lesion D2: Parathyroid adenoma

Lesion E: Parathyroid adenomaBoth thyroid lobe: Multi-focal PTC (3 in the left, 1 in the right)

Lesion F1: PTC(0.5 cm)Lesion F2: Parathyroid adenoma

Lesion G1: PTC(2 × 1.5x1cm)Lesion G2: Thyroid adenoma with cystic degeneration and interstitial fibrosis; Suspected parathyroid carcinoma, wait for final pathologic result

Surgical approach

Left thyroid lobectomy + Dissection of left central cervical lymph nodes + Exploration of left recurrent laryngeal nerve + Right parathyroidectomy

Bilateral parathyroidectomy+ Right thyroid lobectomy + Dissection of right central cervical lymph nodes + Exploration of bilateral recurrent laryngeal nerve

Right thyroid lobectomy + Dissection of right central cervical lymph nodes + Exploration of right recurrent laryngeal nerve + Right parathyroidectomy

Left thyroid lobectomy + Dissection of left central cervical lymph nodes + Exploration of left recurrent laryngeal nerve + Left parathyroidectomy

Total thyroidectomy + Dissection of central cervical lymph nodes + Right parathyroidectomy

Left thyroid lobectomy + Dissection of left central cervical lymph nodes + Exploration of left recurrent laryngeal nerve + Left parathyroidectomy

Total thyroidectomy + Exploration of bilateral recurrent laryngeal nerve + Dissection of right central cervical lymph nodes

Pathological results

Parathyroid

Parathyroid adenoma

Parathyroid adenoma (Lesion B1 & B3)

Parathyroid adenoma

Parathyroid adenoma

Parathyroid adenoma

Parathyroid adenoma

Parathyroid carcinoma

Thyroid

PTMC

PTMC

PTMC

PTC

Multi-focal PTC with metastasis of cervical lymph nodes

PTMC

PTC and Thyroid adenoma

Consistency with US

 Y

Y

Y

Y

Y

Y

Y/N*

  1. Abbreviation: Y Consistent, N Inconsistent. * The results of US report did not mention parathyroid lesion, but it was described in the image features. So it can’t be considered simply to be consistent or inconsistent