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Fig. 2 | BMC Medical Imaging

Fig. 2

From: Apparent diffusion coefficient as an effective index for the therapeutic efficiency of brain chemoradiotherapy for brain metastases from lung cancer

Fig. 2

Two cases were shown below for example the group division: Case 1: Pathologically diagnosed as brain metastases from right lung adenocarcinoma. The maximum diameter of the lesion was 10 mm one week before treatment and the ADC value was 0.653 × 10− 3 mm2/s; the maximum diameter of the lesion was 12 mm and the ADC value was 0.733 × 10− 3 mm2/s after one treatment cycle; the maximum diameter of the lesion was 14 mm and the ADC value was 0.706 × 10− 3 mm2/s after two treatment cycles. According to RECIST criteria, the patient belonged to the invalid group. Case 2: pathologically diagnosed as brain metastases from lung cancer. The lesions on the right occipital lobe were nodular with slightly higher signal intensity on T2WI, slightly lower signal intensity on T1WI, high signal intensity on DWI, and obviously enhanced lesions on contrast-enhanced T1WI. The maximum diameter was 17 mm before treatment and the ADC value was 0.759 × 10− 3 mm2/s; after one treatment cycle, the maximum diameter of the lesion was reduced to about 16 mm, and the ADC value was 1.05 × 10− 3 mm2/s; after two treatment cycles, the enhanced part of the lesion was obviously reduced, with a diameter of 3 mm, and the ADC value was 1.10 × 10− 3 mm2/s, suggesting that the treatment was effective. According to RECIST criteria, this patient belongs to the effective group.

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