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Table 3 Standard uptake values (SUVmax, SUVmean, partial volume corrected SUVmean (cSUVmean) and MTV of malignant lesions at 1h and 3h (mean ± SD, min and max), and the change over time (∆SUV with 95% CI) by patient recurrence status. ∆SUV% and ∆MTV% were calculated by using mean values of 1h and 3h groups. P-values refer to the hypothesis test that the mean difference of the paired observations at 1h and 3h is equal to 0

From: Quantification of FDG-PET/CT with delayed imaging in patients with newly diagnosed recurrent breast cancer

 

1h

3h

∆SUV (3h-1h)

p-value

∆SUV%

All 41 patients with recurrence (337 lesions)

 SUVmax

6.4 ± 3.4

[0.9-19.7]

8.1 ± 4.4

[0.7-29.7]

1.8

[1.5 to 2.1]

< 0.0001

28

 SUVmean

4.0 ± 2.0

[0.5-11.3]

5.1 ± 2.6

[0.4-16.5]

1.1

[1.0 to 1.3]

< 0.0001

28

 cSUVmean

6.5 ± 3.5

[0.7-20.8]

8.8 ± 4.7

[0.5-30.9]

2.3

[1.9 to 2.6]

< 0.0001

35

 MTV (cc)

12.5 ± 42.4

[0.3-562]

10.4 ± 39.9

[0.2-565.5]

−2.1

[− 3.1 to − 1.0]

< 0.0001

− 17

19 patients with local recurrence (21 lesions)

 SUVmax

3.0 ± 1.9

[0.9-8.7]

3.8 ± 3.0

[0.7-12.3]

0.8

[0.2 to 1.4]

0.006

27

 SUVmean

1.9 ± 1.3

[0.5-5.9]

2.4 ± 2.0

[0.4-8.6]

0.5

[0.08 to 0.9]

0.022

25

 cSUVmean

3.2 ± 2.4

[0.7-8.9]

4.4 ± 3.9

[0.5-14.4]

1.2

[0.3 to 2.1]

0.014

36

 MTV (cc)

8.4 ± 10.3

[0.3-33.3]

5.7 ± 5.5

[0.2-22.3]

−2.8

[−6.2 to 0.7]

0.11

−33

22 patients with distant recurrence (316 lesions)

  

 SUVmax

6.6 ± 3.3

[1.2-19.7]

8.4 ± 4.4

[1.2-29.7]

1.8

[1.5 to 2.2]

< 0.0001

28

 SUVmean

4.1 ± 2.0

[0.8-11.3]

5.3 ± 2.6

[0.6-16.5]

1.2

[1.0 to 1.4]

< 0.0001

28

 cSUVmean

6.7 ± 3.5

[0.8-20.8]

9.1 ± 4.6

[0.8-30.9]

2.3

[2.0 to 2.7]

< 0.0001

35

 MTV (cc)

12.8 ± 43.7

[0.4-562.0]

10.7 ± 41.1

[0.2-565.5]

−2.1

[−3.2 to −0.9]

0.001

−16