Table 5 Comparison of TCFAs and ThCFAs at baseline, at follow-up and changes over time
TCFA (n = 63) | ThCFA (n = 34) | p-value | |
|---|---|---|---|
OCT measurements | |||
Fibrous-cap thickness, μm | |||
Baseline | 49.8 ± 8.3 | 81.9 ± 13.4 | <0.001 |
Follow-up | 144.3 ± 80.9 | 186.4 ± 68.0 | 0.011 |
p-value | <0.001 | <0.001 | |
Change | 94.5 ± 79.8 | 104.5 ± 65.4 | 0.593 |
Maximum lipid arc, ° | |||
Baseline | 261.2 ± 66.6 | 204.7 ± 61.4 | <0.001 |
Follow-up | 219.4 ± 74.8 | 182.8 ± 71.3 | 0.022 |
p-value | <0.001 | 0.091 | |
Change | −41.8 ± 50.6 | −22.0 ± 45.8 | 0.060 |
Mean lipid arc, ° | |||
Baseline | 190.8 ± 50.6 | 145.7 ± 39.7 | <0.001 |
Follow-up | 160.6 ± 56.9 | 137.6 ± 50.9 | 0.052 |
p-value | <0.001 | <0.008 | |
Change | −30.3 ± 34.6 | −8.1 ± 27.6 | 0.002 |
Lipid length, mm | |||
Baseline | 10.7 ± 4.9 | 8.4 ± 4.0 | 0.019 |
Follow-up | 10.4 ± 5.1 | 7.3 ± 3.7 | 0.003 |
p-value | 0.218 | 0.005 | |
Change | −0.4 ± 2.3 | −1.1 ± 2.0 | 0.142 |
Lipid index | |||
Baseline | 2037.0 ± 1031.7 | 1083.6 ± 630.2 | <0.001 |
Follow-up | 1727.9 ± 1108.6 | 947.0 ± 705.9 | <0.001 |
p-value | <0.001 | 0.007 | |
Change | 309.1 ± 494.4 | −136.6 ± 304.7 | 0.036 |
CAG measurements | |||
Minimal lumen diameter, mm | |||
Baseline | 2.01 ± 0.58 | 1.99 ± 0.55 | 0.627 |
Follow-up | 1.99 ± 0.55 | 1.98 ± 0.53 | 0.938 |
p-value | 0.52 | 0.559 | |
Change | −0.02 ± 0.28 | 0.02 ± 0.24 | 0.686 |
Diameter stenosis, % | |||
Baseline | 30.7 ± 10.2 | 23.8 ± 9.4 | 0.021 |
Follow-up | 29.5 ± 10.9 | 27.7 ± 10.7 | 0.878 |
p-value | 0.26 | 0.014 | |
Change | −1.14 ± 8.08 | 3.86 ± 8.55 | 0.008 |
Lesion length, mm | |||
Baseline | 12.3 ± 5.6 | 9.37 ± 3.29 | 0.001 |
Follow-up | 12.5 ± 5.4 | 9.98 ± 3.69 | 0.001 |
p-value | 0.37 | 0.155 | |
Change | 0.24 ± 1.88 | 0.61 ± 2.18 | 0.788 |