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Table 2 Serum lipid results, CAG and OCT measurements at baseline and follow-up

From: Comparison of coronary arterial lumen dimensions on angiography and plaque characteristics on optical coherence tomography images and their changes induced by statin

Variables

Baseline

Follow-up

p-value

Serum lipid

 Total cholesterol, mg/dl

198.6 ± 42.2

146.1 ± 40.0

<0.001

 LDL-C, mg/dl

109.4 ± 24.6

73.9 ± 29.2

<0.001

 HDL-C, mg/dl

49.3 ± 12.3

46.7 ± 13.9

0.123

 LDL-C/HDL-C

2.3 ± 0.8

1.7 ± 0.7

<0.001

 Triglycerides, mg/dl

215.7 ± 151.7

140.2 ± 64.3

<0.001

 Apolipoprotein B, mg/dl

89.0 ± 24.1

63.3 ± 25.2

<0.001

OCT quantitative data

 Fibrous-cap thickness, μm

61.1 ± 18.5

159.1 ± 78.9

<0.001

 Maximum lipid arc, °

241.2 ± 69.9

206.4 ± 75.3

<0.001

 Mean lipid arc, °

174.8 ± 51.6

152.5 ± 55.7

<0.001

 Lipid length, mm

9.9 ± 4.7

9.3 ± 4.9

0.010

 Lipid index

1783.4 ± 1038.7

1476.0 ± 1042.7

<0.001

OCT qualitative data, n (%)

 TCFA

63 (64.9%)

13 (13.4%)

<0.001

 Macrophage

71 (73.2%)

58 (59.8)

0.019

 Micro-vessel

44 (45.4)

29 (29.9)

0.004

 Cholesterol crystal

23 (23.7)

10 (10.3)

0.002

 Thrombus

6 (6.2)

0

N/A

 Spotty calcification

25 (26.0)

24 (24.7)

1.000

 Disruption

9 (9.3)

0

N/A

CAG quantitative data

 Minimal lumen diameter, mm

2.0 ± 0.5

2.0 ± 0.5

0.824

 Diameter stenosis, %

28.9 ± 10.5

29.5 ± 11.1

0.530

 Lesion length, mm

11.3 ± 5.1

11.7 ± 5.0

0.069

  1. Data are presented as mean ± SD or n (%). Quantitative data at baseline and at follow-up are compared using paired t test and qualitative data using McNemar test. CAG coronary Angiography, LDL-C low-density lipoprotein cholesterol, HDL-C high-density lipoprotein cholesterol, OCT optical coherence tomography, TCFAs thin-cap fibroatheromas; N/A not applicable. A p-value < 0.05 was considered statistically significant. ° arc of lipid content.