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Table 3 Spinal cord area change over 2 years

From: The effect of intramuscular interferon beta-1a on spinal cord volume in relapsing-remitting multiple sclerosis

  Multiple sclerosis Normal controls MS vs. NC
  p value % change   p value % change   p value
Year 1 - Baseline −0.673 (−2.463, 1.117) 0.435* −0.41 −1.073 (−3.607, 1.460) 0.367* −0.11 0.400 (−3.350, 2.549) 0.780**
Year 2 - Year 1 −0.710 (−2.482, 1.062) 0.406* −0.55 0.486 (−0.768, 1.739) 0.408* 0.15 −1.196 (−0.875, 3.266) 0.245**
Year 2 - Baseline −0.604 (−1.352, 0.144) 0.106* −1.64 −0.360 (−1.576, 0.855) 0.524* −0.78 −0.243 (−1.120, 1.607) 0.712**
  1. Key: mean annualized change in normalized cervical spinal cord area in mm2 (95 % confidence interval) is reported; in addition, the median annualized percent change (%) is reported; the second (earlier) time point was subtracted from the first (later) time point listed; MS relapsing-remitting multiple sclerosis, NC normal controls, *one-sample t-test to assess the within group change; **two-sample t-test to assess the between group difference in changes