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Table 3 Spinal cord area change over 2 years

From: The effect of intramuscular interferon beta-1a on spinal cord volume in relapsing-remitting multiple sclerosis

 

Multiple sclerosis

Normal controls

MS vs. NC

 

p value

% change

 

p value

% change

 

p value

Year 1 - Baseline

−0.673 (−2.463, 1.117)

0.435*

−0.41

−1.073 (−3.607, 1.460)

0.367*

−0.11

0.400 (−3.350, 2.549)

0.780**

Year 2 - Year 1

−0.710 (−2.482, 1.062)

0.406*

−0.55

0.486 (−0.768, 1.739)

0.408*

0.15

−1.196 (−0.875, 3.266)

0.245**

Year 2 - Baseline

−0.604 (−1.352, 0.144)

0.106*

−1.64

−0.360 (−1.576, 0.855)

0.524*

−0.78

−0.243 (−1.120, 1.607)

0.712**

  1. Key: mean annualized change in normalized cervical spinal cord area in mm2 (95 % confidence interval) is reported; in addition, the median annualized percent change (%) is reported; the second (earlier) time point was subtracted from the first (later) time point listed; MS relapsing-remitting multiple sclerosis, NC normal controls, *one-sample t-test to assess the within group change; **two-sample t-test to assess the between group difference in changes