Magnetic resonance enterography changes after antibody to tumor necrosis factor (anti-TNF) alpha therapy in Crohn’s disease: correlation with SES-CD and clinical-biological markers

Table 1 Lennard-Jones anatomic criteria for the diagnosis of CD recognizable by clinical, radiological and pathologic examination

	Clinical/endoscopy	X-ray	Biopsy	Resected specimen
Mouth to anus
Upper gut	+	+	+	+
Anus	+		+	+
Discontinuous	+	+	+	+
Transmural inflammation				+
Fissure		+		+
Abscess	+	+		+
Fistula	+	+		+
Fibrosis/Stenosis	+	+		+
Lymphoid
Ulcers			+	+
Aggregates			+	+
Mucin Retention			+
Granuloma			++	++

^aA diagnosis of Crohn’s disease requires 3 positive findings, or one positive finding with granulomas on histology

ISSN: 1471-2342