Fig. 5

Analysis of incremental value of blocks in the automatic segmentation algorithm. Incremental value of each block in the automatic segmentation algorithm analyzed by bias to manual delineation as %LVM, left panel and by regional agreement as Dice similarity coefficient DSC (right panel). Bias and DSC was calculated with segmentation based on only intensity classification by Expectation Maximization and calculated after the addition of the processing blocks of intensity correction, a priori on myocardium at risk (MaR) and infarct region from late gadolinium enhancement (LGE). For each block of the algorithm the upper limit of the box indicate upper quartile, middle line indicate median, lower limit of box indicate lower quartile, whiskers indicate minimum and maximum points within 1.5 interquartile range and points (+) indicate outliers. Bias zero is shown as dotted black line in the left panel, DSC above of 0.7 indicates good regional agreement [30], and is shown as dotted black line in the right panel. Two sided paired t-test was performed for each block in comparison to previous block and first block, ns: non significant, ***: p < 0.0001