Fig. 4
From: Near-infrared operating lamp for intraoperative molecular imaging of a mediastinal tumor
NIR Imaging of mediastinal mass in vivo and ex vivo. First row: In vivo NIR intraoperative molecular imaging with the use of a typical surgical headlamp. White light, NIR fluorescence and overlay images are shown. Note the false positive NIR fluorescence detected with our intraoperative imaging device when the headlamp is used without a filter. Second row: The addition of the NIR cancelling filter removes the NIR signal emitted from the headlamp and thus reduces false positive fluorescence. Note the tumor is markedly fluorescent in vivo. Third row: With the filtered headlamp still in place, the fluorescent tumor is reimaged ex vivo. Pathology demonstrated thymoma with negative surgical margins