Table 1 Compartment models and their pharmacokinetic parameters and respective units as implemented in our software. Please note that Ktrans = E*Fp and, for the ETM, by definition PS = Ktrans
| Â | Plasma Flow (Fp) (ml/min/100Â ml) | Plasma MTT (s) | Plasma Volume (ml/100Â ml) | Interstitial MTT (s) | Interstitial Volume (ml/100Â ml) | Extraction Fraction (E) (%) | Permeability-surface area product (PS) (ml/min/100Â ml) | Ktrans (ml/min/100Â ml) |
|---|---|---|---|---|---|---|---|---|
1CP | x | x | x | Â | Â | Â | Â | Â |
2CUM | x | x | x | Â | Â | x | x | x |
2CFM | x | x | x | x | Â | x | x | x |
2CXM | x | x | x | x | x | x | x | x |
ETM | Â | Â | x | x | x | Â | x | x |