Combined PET/CT-perfusion in patients with head and neck cancers might predict failure after radio-chemotherapy: a proof of concept study

Table 3 Comparison between Pre- and Posttherapeutic CTP-values in patients with recurrence and recurrence free patients

		Pre	SD^b	Post	SD^b	Δ (%)
BF (ml/100 mg/min)	Disease-free	171.2	123.7	70.2	34.11	−59.0
BF (ml/100 mg/min)	Recurrence	267.4	161.7	67.1	22.4	−74.9
BV (ml/100 mg)	Disease-free	8.4	7.4	4.7	1.7	−34.9
BV (ml/100 mg)	Recurrence	40.9	39.2	5.3	0.7	−88.4
MTT (sec.)	Disease-free	6.1	5.0	7.4	2.6	35.9
MTT (sec.)	Recurrence	8.2	3.5	7.8	3.9	−4.5
SUVmax	Disease-free	9.3	4.0	3.2^a	1.3	−65.5^a
SUVmax	Recurrence	10.1	4.7	6.0^a	1.6	−40.1^a
SUVmean	Disease-free	5.7	3.0	2.0^a	0.8	−64.7^a
SUVmean	Recurrence	6.2	3.0	3.6^a	1.2	−41.4^a
TLG	Disease-free	57.8 × 10^3a	66.6 × 10³	29.8 × 10^3a	20.3 × 10³	−48.4^a
TLG	Recurrence	79.3 × 10^3a	51.4 × 10³	21.8 × 10^3a	5.8 × 10³	−70.3^a

Significant differences are marked with ^a. Significant differences: TLG differed significantly in the pre-therapeutic scans. The Δ for SUVmax/mean and TLG differed significantly between patients with recurrence and those recurrence free. The post-therapeutic values for SUVmax/mean and TLG differed significantly between the patients that died and the recurrence free. Significant correlations: ΔSUVmax and ΔTLG (p <0.01) and ΔSUVmax and ΔSUVmean (p <0.05). ^bStandard deviation (SD)

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