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Table 3 Description of tested protocols

From: Reproducibility of brain metabolite concentration measurements in lesion free white matter at 1.5 T

Protocol no

Glx

Glu/Gln

GABA

Li’s

Base

com. dam.

full eval.

0

free

25 ms

1

free

free

free

25 ms

1a

free

free

25 ms

2

free

10 ms

3

free

free

free

10 ms

3a

free

free

10 ms

4

free

25 ms

5

free

free

free

25 ms

5a

free

free

25 ms

6

free

10 ms

+

7

free

free

free

10 ms

7a

free

free

10 ms

8

Naa

25 ms

9a

Naa

free

25 ms

10

Naa

10 ms

+

11a

Naa

free

10 ms

12

free

25 ms

+

+

13a

free

free

25 ms

+

+

14

free

10 ms

+

+

15a

free

free

10 ms

+

16

Naa

25 ms

+

17a

Naa

free

25 ms

+

18

Naa

10 ms

+

+

19a

Naa

free

10 ms

+

+

20

Naa

free

10 ms

+ Myo free

  1. Amplitude and frequency of Naa, Cre3, Cre2, Cho and Myo are always fit parameters. The damping for each metabolite is independent in case of a “–” in column “common damping” and equal for all metabolites except the lipids and Cre2 in case of a “+”. The damping of these metabolites can be adjusted between 1 and 10 Hz. The damping of lipids is always independent with range from 1 to 25 Hz. “full evaluation” means all 54 pairs of spectra were used for rn evaluation, whereas in other cases only one spectrum of each subject (11 examples, left brain hemisphere of first investigation) was used for an estimation of rn. Naa means the frequency of Glu/Gln is fixed relative to the detected frequency of Naa. The numbering follows the historical order of evaluation and therefore needs in some cases an index “a” for later evaluated protocols