Fig. 1
From: Multiple paragangliomas of head and neck associated with hepatic paraganglioma: a case report
Radiologic, histologic and immunophenotypic features of HNPGs in the patient. a Coronal contrast enhanced multiple-planner reconstruction (MPR) image for a better visualization of the relationship between the masses and the carotid artery. Bilateral masses were detected at the bifurcation of both sides of the carotid artery, showing intense but heterogeneous enhancement with the internal and external carotid arteries surrounded and pushed anteriorly. b Computed tomographic angiography (CTA) image showing the tumor vascularity. c The axial gadolinium-enhanced T1-weighted image showing intense enhancement on the masses. d, e Digital subtraction angiography (DSA) showing highly vascularized masses occupying and deforming the bifurcation of both the right (d) and left (e) side of the carotid artery. f The postoperative CTA image showing the right mass excised and stent implatation in bilateral internal carotid arteries. g, h Haematoxylin and eosin staining of the HNPG specimen showing the nested (Zellballen) pattern of neoplastic cells and their neuroendocrine appearance (g: magnification, × 200; h: magnification, × 400). i, j Immunohistochemical staining for synaptophysin (i) and S-100 (j) highlighting the chief and sustentacular cells, respectively (magnification, × 400)