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Table 2 4 studies on measurements of left ventricular strain at rest to predict CAD+ using coronary angiogram as reference

From: Diagnostic accuracy of left ventricular longitudinal function by speckle tracking echocardiography to predict significant coronary artery stenosis. A systematic review

Study

n

CAG

GLS (%)

p CAD+ vs CAD-

TLS (%)

pCAD+ vs CAD-

AUC for CAD+ (95 % CI)

Cut-off

Sensitivity

Specificity

Montgomery [24]

123

CAD+ n = 56a

−16.8 ± 3,2

   

GLS 0.72 (0.63-0.82)

- 17.8 %

66 %

76 %

  

CAD- n = 67

−19.1 ± 3.4

0.0002

  

TLS 0.73 (0.62 - 0.83)

- 18.3 %

69 %

70 %

109

LAD+ n = 35c

−19 ± 2.8

 

−18.68 ± 3.3

     
 

LAD- n = 74

−17.5 ± 2.7

0.0001

−21.14 ± 3.3

     

Smedsrud [25]

86

CAD+ n = 43a

−17.7 ± 3.0

 

−17.9 ± 3.5

 

GLS 0.68 (0.56-0.79)

−17.4 %

51 %

81 %

  

CAD- n = 43

−19.5- ± 2.6

0.003

−20.1 ± 2.9

0.015

TLS 0.67 (0.52-0.82)

n.a.

n.a.

n.a.

Biering-Sørensen [26]

293

CAD+ n = 107b

−17.1 ± 2.5b

   

GLS 0.68 (0.62-0.74)d

- 18.4 %

74 %

58 %

 

CAD- n = 186

- 18.8 ± 2.6

<0.001

      

Shimoni [27]

97

CAD+ n = 69a

−17.3 ± 2.4

 

−9.1 ± 3.2

 

GLS 0.80

−19.7 %

81 %

67 %

  

CAD- n = 28

−20.8 ± 2.3

<0.001

−12.9 ± 2.3

<0.001

TLS 0.75

−12.6 %

77 %

68 %

  1. Abbreviations and definitions: CAD+ was defined as ≥ 50 % stenosis a in one or more coronary arteries and as ≥ 70 % luminal area reductionb
  2. LAD: Left anterior desending csubset of 109 patients where TLS in the LAD territory was performed. d GLS from 12 segments. TLS = territorial longitudinal strain, defined specifically in the text from each study