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Table 1 Layer-specific left ventrcular strain measurements at rest using CAG as reference for CAD

From: Diagnostic accuracy of left ventricular longitudinal function by speckle tracking echocardiography to predict significant coronary artery stenosis. A systematic review

 

Strain values (%)

Differences endo-epic. strain

 

Study

Indication

CAG

CAD+

CAD-

p-value

CAD+

CAD-

p-value

AUC for CAD+, TLS/GCS (%)

Sarvari [23]

Suspected NSTE-ACS n = 77

CAD+ n = 49

TLS: −14.0 ± 3.3

−19.2 ± 2.2

<0.001

Δ2.4 ± 3.6

Δ5.3 ± 2.1

<0.001

Endocardial: 0.91/0.85

CAD- n = 28

GCS: −19.3 ± 4.0

- 24.3 ± 3.4

<0.001

Δ2.4 ± 3.7

Δ10.4 ± 3.0

<0.001

Mid-myocardial: 0.91/0.87

 

GLS: −15.3 ± 2.2

−19.2 ± 2.2

<0.001

Δ2.4 ± 3.8

Δ5.3 ± 2.1

<0.001

Epicardial: 0.79/0.68

  1. Strain values and differences between andocardial and epicardial strain are presented as mean ± SD
  2. NSTE-ACS Non-ST elevation acute coronary syndrome, CAG Coronary angiography, CAD+ Coronary artery disease, defined as coronary artery stenosis ≥ 50 %, TLS Territorial longitudinal strain, GCS Global circumferential strain, endo endocardial, epic epicardial, AUC Area under the curve for ROC analysis of prediction of CAD being present or not