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Fig. 5 | BMC Medical Imaging

Fig. 5

From: Evaluation of 11C-Acetate and 18 F-FDG PET/CT in mouse multidrug resistance gene-2 deficient mouse model of hepatocellular carcinoma

Fig. 5

LPA variant profile is modulated prior to HCC emergence in MDR2−/− mice. a) Serum levels of LPA and LPC variants were determined by LC/MS. There was a significant increase in 18:2 LPA and 20:4 LPA in MDR2−/− mice prior to the emergence of HCC at 12 mo. LPA variant levels were maximal at 12 mo. b) Calculation of the 20:4 LPC/20:4 LPA ratios showed a dramatic change indicative of increased ATX activity

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BMC Medical Imaging

ISSN: 1471-2342

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