Figure 8From: Evaluating regional blood spinal cord barrier dysfunction following spinal cord injury using longitudinal dynamic contrast-enhanced MRI Histology images of an injured SC on day 3: a) H&E-stained section with arrows denotes extravasated red blood cells. b-d) higher magnifications of adjacent section stained with the endothelial marker, CD34. The square windows marked with numbers 1, 2 and 3 were selected to show vasculature and BSCB integrity therein. b) Sparse, intact vasculature (arrows). c) Disrupted vasculature with diffusion of immunostaining due to damaged BSCB. d) Disrupted vessels and tissue vacuolization due to edema from the leaky BSCB (arrows).Back to article page